The red vine is used nowadays in herbal medicine to fight against circulatory problems, treat venous insufficiency, the feeling of heavy legs and edemas. It helps to improve the resistance of blood vessels and reduce their permeability. These benefits with veinotonic, angioprotective and anti-oedematous actions make grape vine an excellent health ingredient.
The red colour of the leaves of Vitis vinifera L. is indeed a sign of an optimal content of active principles, in particular flavonoids. Rutin, the pigment responsible for the colouring of the leaves, contributes to good circulatory comfort and thus relieves the feeling of heavy legs as well as for the whole venous circulation of the body. Like other bioflavonoids, rutin promotes the absorption of Vitamin C and therefore helps to preserve good vitality. These antioxidant compounds contain quercetin, quercetol, kaempferol, anthocyanosides and proanthocyanidins, which also have venous and capillary tonic effects.
Flavonoid derivatives, oligo-proanthocyanidin tannins are also present in the vine seed envelope. The vine tannins, the proanthocyanidols, have astringent and diuretic virtues. In addition to their antioxidant capacity, certain polyphenols of red vine such as quercetin are capable of reducing inflammatory reactions. They also have many protective effects, particularly in the fight against chronic venous insufficiency. Resveratrol is the famous polyphenol contained in the red vine, in particular in the skin of the grape and rich in health benefits in particular for the prevention of cardiovascular diseases.
Essential plant to fight against tingling, swelling and feeling of heavy legs, the red vine and its phytonutrients also relieve hemorrhoids. It is therefore recommended for prevention or support for good circulatory comfort. It is now found in different galenics: mother tincture, dry leaf powder, fresh plant extract or dry extract. Among these formulations, there are specific preparations including food supplements and red vine infusions.
 Monsieur R, Van Snick G. [Efficacy of the red vine leaf extract AS 195 in Chronic Venous Insufficiency]. Schweiz Rundsch Med Prax. 2006 Jan 25;95(6):187-90.
 Schaefer E, Peil H, et al. Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial. Arzneimittelforschung. 2003;53(4):243-6.
 BOUQUET, Florence. Propriétés pharmacologiques de la vigne rouge. Exercise Thesis. Lille University, France, 2010.
 SANTÉ, A. Z. Oligo-proanthocyanidines.
 Kalus U, Koscielny J, et al. Improvement of cutaneous microcirculation and oxygen supply in patients with chronic venous insufficiency by orally administered extract of red vine leaves AS 195: a randomised, double-blind, placebo-controlled, crossover study. Drugs R D. 2004;5(2):63-71.